SCHEMBL162037

SCHEMBL162037

CN[C@H](CCC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 9/20 0.61
NAALAD2 Q9Y3Q0 2/20 0.61
RIMKLA Q8IXN7 1/20 0.61
GGH Q92820 1/20 0.57
ANPEP P15144 1/20 0.52
ENPEP Q07075 1/20 0.52
CYP1A2 P05177 1/20 0.50
TET2 Q6N021 3/20 0.46
KDM4A O75164 2/20 0.46
KDM4C Q9H3R0 2/20 0.46
KDM2A Q9Y2K7 2/20 0.46
TET3 O43151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162038 1.00 FOLH1 (0.61) FOLH1NAALAD2RIMKLAGGHANPEP
SCHEMBL31599178 1.00 FOLH1 (0.61) FOLH1NAALAD2RIMKLAGGHANPEP
SCHEMBL180085 1.00 FOLH1 (0.61) FOLH1NAALAD2RIMKLAGGHANPEP
Ammonia Solution, Strong SCHEMBL10700813 0.98 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHANPEP
Hydrochloric Acid SCHEMBL27904743 0.98 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHANPEP
Hydrochloric Acid SCHEMBL5321442 0.98 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHANPEP
SCHEMBL10830382 0.98 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHANPEP
SCHEMBL18575228 0.98 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHANPEP
SCHEMBL28160359 0.98 FOLH1 (0.59) FOLH1NAALAD2RIMKLAGGHANPEP
SCHEMBL29973847 0.92 FOLH1 (0.53) FOLH1NAALAD2RIMKLAGGHANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20220162261-A1 NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS PROTAGONIST THERAPEUTICS, INC. 2022-05-26 US claimed
US-9695191-B2 Conformationally constrained, fully synthetic macrocyclic compounds POLYPHOR AG (CH) 2017-07-04 US claimed
EP-2462147-B1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2014-11-12 EP claimed
US-20120202821-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2012-08-09 US claimed
US-20090215895-A1 Therapeutic and carrier molecules PEPLIN BIOLIPIDS PTY LTD (AU) 2009-08-27 US claimed
EP-1718602-A4 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2007-12-12 EP claimed
US-7256172-B1 Method of treatment and agents useful for same THE UNIVERSITY OF MELBOURNE (AU) 2007-08-14 US claimed
EP-1718602-A1 THERAPEUTIC AND CARRIER MOLECULES Peplin Biolipids Pty Ltd. (AU) 2006-11-08 EP claimed
WO-2005073164-A1 THERAPEUTIC AND CARRIER MOLECULES PEPLIN BIOLIPIDS PTY LTD (AU) 2005-08-11 WO claimed
US-20260140060-A1 COLORIMETRIC DETECTION OF A VIRAL INFECTION RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-05-21 US disclosed
US-20260124281-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF PARATHYROID HORMONE ENTERA BIO LTD. (IL) 2026-05-07 US disclosed
WO-2026085582-A1 PROTEIN CAGES THE UNIVERSITY OF SYDNEY (AU) 2026-04-30 WO disclosed
EP-4731266-A1 NANOPARTICLE COMPOSITIONS ASSOCIATED WITH PEPTIDES The Regents of the University of Michigan (US) 2026-04-29 EP disclosed
US-20260109870-A1 PEPTIDE-BASED NON-CRYSTALLINE MATERIALS AND COMPOSITIONS AND PROCESSES FOR OBTAINING SAME RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-04-23 US disclosed
WO-1994011388-A1 SUPPORT FOR THE SYNTHESIS OF MODULAR POLYMERS CHIRON MIMOTOPES PTY. LTD. (AU) 1994-05-26 WO disclosed
WO-1994003483-A1 ENDOTHELIN RECEPTOR-BINDING COMPOUNDS CHIRON CORPORATION (US) 1994-02-17 WO disclosed
EP-0434979-A1 Peptide derivatives useful as antagonists of bombesin and gastrin-releasing peptide MERRELL DOW PHARMACEUTICALS INC. (US) 1991-07-03 EP disclosed
EP-0211223-A2 Spherical grains of poly(alpha-amino acid)and production method thereof Juridical Foundation The Chemo-Sero-Therapeutic Research Institute (JP) 1987-02-25 EP disclosed
US-3985617-A IMMOBILIZATION OF BIOLOGICALLY ACTIVE PROTEINS WITH A POLYPEPTIDE AZIDE AJINOMOTO CO., INC. (JA) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215895-A1 Therapeutic and carrier molecules PHKG1, PHKG2, DGKB FOLH1 2178/4885NAALAD2 4393/4885RIMKLA 4048/4885
US-20120202821-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS HTR2B, MC1R, HTR1A FOLH1 1731/4885NAALAD2 4205/4885RIMKLA 1666/4885
US-20260124281-A1 FORMULATIONS COMPRISING ACID-NEUTRALIZING POLYMER FOR ORAL ADMINISTRATION OF PARATHYROID HORMONE PTH1R, FGF23, PTMS FOLH1 847/4885NAALAD2 2085/4885RIMKLA 4027/4885
US-20260109870-A1 PEPTIDE-BASED NON-CRYSTALLINE MATERIALS AND COMPOSITIONS AND PROCESSES FOR OBTAINING SAME NONO, NGLY1, PTMS FOLH1 1584/4885NAALAD2 921/4885RIMKLA 3165/4885
US-20260140060-A1 COLORIMETRIC DETECTION OF A VIRAL INFECTION CTSL, CPA4, ACE2 FOLH1 308/4885NAALAD2 191/4885RIMKLA 2031/4885
US-20220162261-A1 NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS EPCAM, VCAM1, ITGB7 FOLH1 2497/4885NAALAD2 1441/4885RIMKLA 4036/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 FOLH1 1381/4885NAALAD2 87/4885RIMKLA 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.