Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389499 | 0.95 | FFAR1 (0.47) | FFAR1KMT2AFFAR4MAPTLTB4R | |
| SCHEMBL2743314 | 0.95 | KMT2A (0.47) | FFAR1KMT2AL3MBTL1LTB4RTSHR | |
| SCHEMBL11827946 | 0.92 | FFAR1 (0.49) | FFAR1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL69788 | 0.87 | FFAR1 (0.48) | FFAR1KMT2AFFAR4MAPTKDM4E | |
| SCHEMBL11838668 | 0.86 | KMT2A (0.48) | FFAR1KMT2AMAPTL3MBTL1 | |
| SCHEMBL5490631 | 0.83 | PDE4B (0.53) | FFAR1FFAR4MAPTKDM4EALDH1A1 | |
| SCHEMBL28892808 | 0.82 | KMT2A (0.48) | FFAR1KMT2AL3MBTL1TSHR | |
| SCHEMBL10993868 | 0.81 | FFAR1 (0.49) | FFAR1MAPTCYP1A2SMN1; SMN2LTB4R | |
| SCHEMBL5501292 | 0.80 | FFAR1 (0.50) | FFAR1LTB4R | |
| SCHEMBL16428761 | 0.79 | FFAR1 (0.50) | FFAR1KMT2AFFAR4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856063-A1 | 5-PHENYL-PENTANOIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS FOR THE TREATMENT OF ASTHMA AND OTHER DISEASES | Ranbaxy Laboratories Limited (IN) | 2007-11-21 | — | — | EP | claimed |
| WO-2006090235-A1 | 5-PHENYL-PENTANOIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS FOR THE TREATMENT OF ASTHMA AND OTHER DISEASES | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-31 | — | — | WO | claimed |