Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402189 | 0.88 | KMT2A (0.52) | KMT2ACNR1CNR2SLC6A3L3MBTL1 | |
| SCHEMBL2743314 | 0.87 | KMT2A (0.47) | KMT2AL3MBTL1TSHRFFAR1 | |
| SCHEMBL279848 | 0.84 | KMT2A (0.44) | KMT2ATBXA2RL3MBTL1TSHRFFAR1 | |
| SCHEMBL2538851 | 0.82 | TBXAS1 (0.47) | TBXA2RCNR1CNR2SLC6A3TBXAS1 | |
| SCHEMBL5494762 | 0.82 | FFAR1 (0.48) | KMT2AL3MBTL1TSHRFFAR1 | |
| SCHEMBL69788 | 0.82 | FFAR1 (0.48) | KMT2ATBXAS1L3MBTL1TSHRFFAR1 | |
| SCHEMBL5692956 | 0.82 | TBXAS1 (0.63) | TBXA2RCNR1CNR2SLC6A3TBXAS1 | |
| Adipic Acid SCHEMBL3804252 | 0.81 | KMT2A (0.61) | KMT2AL3MBTL1TSHRFFAR1RAB9A | |
| Adipic Acid SCHEMBL27731397 | 0.81 | KMT2A (0.61) | KMT2AL3MBTL1TSHRFFAR1RAB9A | |
| SCHEMBL67079 | 0.81 | TBXA2R (0.58) | TBXA2RSLC6A3TBXAS1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112574208-B | Substituted fused tricyclic derivatives, compositions and uses thereof | 深圳市塔吉瑞生物医药有限公司 | 2022-09-13 | — | — | CN | disclosed |