SCHEMBL5494860

SCHEMBL5494860

FC(F)C(F)(F)C(F)(F)C(F)(F)CI

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25684962 0.92 TSHR (0.33) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL30095977 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL3919509 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL30096012 0.90 TSHR (0.36) KDM4ETSHRTDP1CYP1A2CYP2C19
SCHEMBL24421385 0.85
SCHEMBL25685339 0.85
SCHEMBL24421382 0.82
SCHEMBL25685471 0.80
SCHEMBL25761953 0.80
SCHEMBL10868933 0.79 KDM4E (0.31) KDM4ETSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070172646-A1 Liquid resin composition, cured film and laminate JSR CORPORATION (JP) 2007-07-26 US disclosed
EP-1491562-B1 FLUORINATED OLEFIN POLYMER, CURABLE RESIN COMPOSITION, AND ANTIREFLECTION FILM JSR CORP (JP) 2007-01-17 EP disclosed
EP-1624022-A1 LIQUID RESIN COMPOSITION, CURED FILM AND LAMINATE JSR Corporation (JP) 2006-02-08 EP disclosed
US-20040209919-A1 Stabilized pharmaceutical composition TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-10-21 US disclosed
US-6749864-B2 BENZIMIDAZOLE ANTIULCER AGENTS STABILIZED BY INCORPORATION OF AN EFFECTIVE AMOUNT OF A BASIC INORGANIC SALT OF MAGNESIUM, CALCIUM, POTASSIUM AND SODIUM TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-06-15 US disclosed
US-20030211155-A1 Stabilized pharmaceutical composition TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-11-13 US disclosed
EP-0953584-B1 Olefin polymer, process for manufacturing the same, curable resin composition, and antireflection coating JSR CORP (JP) 2002-12-18 EP disclosed
US-6495293-B1 IMPROVEMENT IN THE DIFFUSIVITY OF ELECTROLYTE; LITHIUM BATTERY HITACHI, LTD. (JP) 2002-12-17 US disclosed
US-20020137771-A1 Stabilized pharmaceutical composition TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-09-26 US disclosed
US-6380234-B1 HOMOGENITY MIXING, GRANULATION, ENTERIC COATING TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-04-30 US disclosed
US-5639478-A ENTERIC COATING OF A MIXTURE OF AN ANTIULCER AGENT AND ALKALINE METAL SALT STABILIZER TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-06-17 US disclosed
EP-0446961-B1 Stabilized pharmaceutical composition and its production TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-06-19 EP disclosed
US-5433959-A Antisecretory agent such as lansoprazole stabilized by basic inorganic salts TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-07-18 US disclosed
EP-0423748-B1 Stabilized pharmaceutical composition and its production TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-08-24 EP disclosed
EP-0237200-B1 USE OF BASIC INORGANIC SALTS OF MAGNESIUM OR CALCIUM FOR THE STABILISATION OF BENZIMIDAZOLE DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 1992-07-01 EP disclosed
US-5093132-A Antiulcer benzimidazole derivative with basic alkali metal or alkaline earth metal compound TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-03-03 US disclosed
EP-0446961-A2 Stabilized pharmaceutical composition and its production Takeda Chemical Industries, Ltd. (JP) 1991-09-18 EP disclosed
US-5045321-A Antiulcer compound lansoprazole or omeprazole with magnesium and/or calcium salt; tablets or granules TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-03 US disclosed
EP-0423748-A1 Stabilized pharmaceutical composition and its production Takeda Chemical Industries, Ltd. (JP) 1991-04-24 EP disclosed
EP-0237200-A2 Use of basic inorganic salts of magnesium or calcium for the stabilisation of benzimidazole derivatives Takeda Chemical Industries, Ltd. (JP) 1987-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020137771-A1 Stabilized pharmaceutical composition CACNA1E, CA2, CACNA1I KDM4E 815/4885TSHR 3200/4885TDP1 4370/4885
US-20030211155-A1 Stabilized pharmaceutical composition CACNA1E, CA2, CACNA1I KDM4E 506/4885TSHR 3121/4885TDP1 4302/4885
US-20040209919-A1 Stabilized pharmaceutical composition CACNA1E, CA2, CACNA1I KDM4E 815/4885TSHR 3200/4885TDP1 4370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.