SCHEMBL5494889

SCHEMBL5494889

COC(=O)[C@@H]1CC(C)CN1C(C)=O

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 13/20 0.67
ANPEP P15144 8/20 0.67
PEPD P12955 2/20 0.52
ATM Q13315 1/20 0.46
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.38
XPNPEP1 Q9NQW7 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10027150 1.00 MMP2 (0.67) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL10027149 1.00 MMP2 (0.67) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL3788772 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL3783083 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL3788774 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL10793356 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL3784082 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL3783080 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL3789111 0.85 MMP2 (0.72) MMP2ANPEPPEPDATMALDH1A1
SCHEMBL12395381 0.84 PEPD (0.55) MMP2ANPEPPEPDALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159622-A1 COLLAGEN MIMICS WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-05-25 US disclosed
US-11390662-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-07-19 US disclosed
US-10329341-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-25 US disclosed
US-20180030115-A1 COLLAGEN MIMICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-02-01 US disclosed
US-9758569-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-09-12 US disclosed
US-20070275897-A1 Collagen mimics NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US disclosed