Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.59 |
| ▸ | TERT | O14746 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934242 | 0.81 | RAB9A (0.61) | CA1CA2TERTTAAR1LTA4H | |
| SCHEMBL3659521 | 0.81 | CA1 (0.61) | CA1CA2TERTTAAR1LTA4H | |
| SCHEMBL6934094 | 0.79 | GAA (0.61) | CA1CA2POLBMEN1KMT2A | |
| SCHEMBL7813510 | 0.79 | CA1 (0.59) | CA1CA2TERTTAAR1LTA4H | |
| SCHEMBL8039353 | 0.79 | POLB (0.73) | CA1CA2TERTPOLBMEN1 | |
| SCHEMBL15061798 | 0.79 | CA1 (0.59) | CA1CA2TERTTAAR1POLB | |
| SCHEMBL7800005 | 0.79 | NPC1 (0.63) | POLBMEN1KMT2ALMNAMAPT | |
| SCHEMBL7445670 | 0.79 | KMT2A (0.73) | CA1CA2TERTTAAR1LTA4H | |
| SCHEMBL2475631 | 0.79 | NPC1 (0.61) | CA1CA2TERTTAAR1LTA4H | |
| SCHEMBL1356115 | 0.79 | KMT2A (0.50) | POLBMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294615-B1 | Compounds that associate on the intermolecular level and aggregate bodies that contain them | Bovin, Nikolai Vladimirovich (RU) | 2007-11-13 | — | — | US | disclosed |
| EP-1223984-A2 | COMPOUNDS THAT ASSOCIATE ON THE INTERMOLECULAR LEVEL AND AGGREGATE BODIES THAT CONTAIN THEM | Syntesome Gesellschaft Fur Med. Biochemie M.B.H. (DE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001002018-A2 | COMPOUNDS THAT ASSOCIATE ON THE INTERMOLECULAR LEVEL AND AGGREGATE BODIES THAT CONTAIN THEM | SYNTESOME GESELLSCHAFT FÜR MEDIZINISCHE BIOCHEMIE MBH (DE) | 2001-01-11 | — | — | WO | disclosed |