Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549314 | 1.00 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL549532 | 1.00 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL2700381 | 1.00 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL549313 | 1.00 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL2700378 | 1.00 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL551021 | 0.97 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL2698085 | 0.97 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL549383 | 0.97 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL549415 | 0.97 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 | |
| SCHEMBL551561 | 0.97 | CRBN (0.46) | CRBNKMT2AALDH1A1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110581-B2 | Lactam compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2012-02-07 | — | — | US | claimed |