Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2701334 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL549962 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL549566 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL549961 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2701336 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL2701931 | 0.99 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL549274 | 0.99 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL549275 | 0.99 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL551743 | 0.99 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR | |
| SCHEMBL551742 | 0.99 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110581-B2 | Lactam compounds and their use as pharmaceuticals | INCYTE CORPORATION (US) | 2012-02-07 | — | — | US | claimed |