SCHEMBL5495984

SCHEMBL5495984

CC(O)C(N)C(=O)N(C(=O)C(N)C(C)O)C(C(=O)O)C(C)O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.39
TP53 P04637 1/20 0.35
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396689 0.77 SLC7A5 (0.39) SLC7A5SLC1A3SLC1A2SLC1A1
SCHEMBL31116850 0.77 SLC7A5 (0.52) SLC7A5TP53SLC1A3SLC1A2SLC1A1
SCHEMBL28528567 0.76 SLC7A5 (0.46) SLC7A5TP53SLC1A3SLC1A2SLC1A1
SCHEMBL28528578 0.76 SLC7A5 (0.46) SLC7A5TP53SLC1A3SLC1A2SLC1A1
SCHEMBL7529258 0.76 SLC7A5 (0.41) SLC7A5TP53SLC1A3SLC1A2SLC1A1
SCHEMBL7529252 0.76 SLC7A5 (0.41) SLC7A5TP53SLC1A3SLC1A2SLC1A1
SCHEMBL6009512 0.73 OR51E2 (0.44) TP53
SCHEMBL28209795 0.73 TP53 (0.41) TP53
SCHEMBL28209796 0.73 TP53 (0.41) TP53
Threonine SCHEMBL14946556 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100443592-C Process for fermentative preparation of L-threonine DEGUSSA (DE) 2008-12-17 CN disclosed
EP-1285075-B1 PROCESS FOR THE FERMENTATIVE PREPARATION OF L-THREONINE DEGUSSA (DE) 2007-02-28 EP disclosed
US-6913909-B2 Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria DEGUSSA AG (DE) 2005-07-05 US disclosed
CN-1430672-A Process for fermentative preparation of L-threonine DEGUSSA (DE) 2003-07-16 CN disclosed
US-20030049802-A1 Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria DEGUSA HULS AKTIENGESELSCHAFT 2003-03-13 US disclosed
EP-1285075-A1 PROCESS FOR THE FERMENTATIVE PREPARATION OF L-THREONINE Degussa AG (DE) 2003-02-26 EP disclosed
US-20020168731-A1 New nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria DEGUSSA-HULS AG 2002-11-14 US disclosed
US-20020155551-A1 Process for the fermentative preparation of L-threonine DEGUSSA AG 2002-10-24 US disclosed
US-20020146781-A1 Nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria DEGUSA HULS AKTIENGESELSCHAFT 2002-10-10 US disclosed
US-20020107378-A1 New nucleotide sequences coding for the thrE gene and process for the enzymatic production of L-threonine using coryneform bacteria DEGUSA HULS AKTIENGESELSCHAFT 2002-08-08 US disclosed
US-6410705-B1 NUCLEOTIDE SEQUENCES CODING ENZYMATIC POLYPEPTIDE FOR USE IN THE GENERATION OF THREONINE; FOR USE IN PREPARATION OF ANIMAL NUTRIENTS, HUMAN MEDICINE AND PHARMACOLOGY DEGUSSA HULS AKTIENGESELLSCHAFT 2002-06-25 US disclosed
WO-2001092545-A1 PROCESS FOR THE FERMENTATIVE PREPARATION OF L-THREONINE DEGUSSA AG (DE) 2001-12-06 WO disclosed
CN-1291651-A New nucleotide sequence of encode thrE gene and method of producing L-threonine using corynebacterium enzyme DEGUSSA (DE) 2001-04-18 CN disclosed