Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529258 | 1.00 | SLC7A5 (0.41) | SLC7A5DPP4TP53ADAMTS4SLC1A3 | |
| Hydrochloric Acid SCHEMBL954589 | 0.78 | SLC7A5 (0.38) | SLC7A5DPP4TP53 | |
| SCHEMBL23118418 | 0.77 | ADAMTS4 (0.35) | SLC7A5TP53ADAMTS4 | |
| SCHEMBL5495984 | 0.76 | SLC7A5 (0.39) | SLC7A5TP53SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8585917 | 0.74 | SLC7A5 (0.53) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23821149 | 0.73 | SLC1A2 (0.41) | SLC7A5DPP4SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28906020 | 0.73 | SLC7A5 (0.39) | SLC7A5TP53ADAMTS4SLC1A3SLC1A2 | |
| SCHEMBL3983698 | 0.72 | DPP4 (0.36) | SLC7A5DPP4TP53 | |
| SCHEMBL4157374 | 0.72 | DPP4 (0.36) | SLC7A5DPP4TP53 | |
| SCHEMBL4155785 | 0.72 | DPP4 (0.36) | SLC7A5DPP4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1190066-A2 | METHOD OF MODIFYING PEPTIDE SYNTHETASES SUCH THAT THEY CAN N-METHYLATE THEIR SUBSTRATE AMINO ACIDS | Actinodrug Pharmaceuticals GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000077220-A2 | METHOD OF MODIFYING PEPTIDE SYNTHETASES SUCH THAT THEY CAN N-METHYLATE THEIR SUBSTRATE AMINO ACIDS | ACTINODRUG PHARMACEUTICALS GMBH (DE) | 2000-12-21 | — | — | WO | disclosed |