SCHEMBL5496029

SCHEMBL5496029

C1=COCC1.[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11126638 0.96 CA1 (0.30)
Fluoride SCHEMBL27474380 0.96
SCHEMBL16851 0.96
Hydrochloric Acid SCHEMBL28169082 0.93
SCHEMBL29401883 0.93
Water SCHEMBL8763582 0.93
SCHEMBL28146323 0.93
SCHEMBL28610358 0.93
Hydrogen Peroxide SCHEMBL11746861 0.90
Benzene SCHEMBL28775548 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208984-A1 BIVALENT LIGANDS TO UNDERSTAND DIMERIZATION OF THE MU OPIOID RECEPTOR AND THE CHEMOKINE RECEPTOR CCR5 IN NEUROLOGICAL DISORDERS VIRGINIA COMMONWEALTH UNIVERSITY 2024-06-27 US disclosed
EP-4313051-A1 BIVALENT LIGANDS TO UNDERSTAND DIMERIZATION OF THE MU OPIOID RECEPTOR AND THE CHEMOKINE RECEPTOR CCR5 IN NEUROLOGICAL DISORDERS Virginia Commonwealth University (US) 2024-02-07 EP disclosed
WO-2022212471-A1 BIVALENT LIGANDS TO UNDERSTAND DIMERIZATION OF THE MU OPIOID RECEPTOR AND THE CHEMOKINE RECEPTOR CCR5 IN NEUROLOGICAL DISORDERS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2022-10-06 WO disclosed
EP-3840751-A1 NON-PEPTIDE OPIOID RECEPTOR MODULATORS Virginia Commonwealth University (US) 2021-06-30 EP disclosed
US-11014933-B2 Non-peptide opioid receptor modulators VIRGINIA COMMONWEALTH UNIVERSITY (US) 2021-05-25 US disclosed
US-20200216458-A1 NON-PEPTIDE OPIOID RECEPTOR MODULATORS VIRGINIA COMMONWEALTH UNIVERSITY 2020-07-09 US disclosed
WO-2020041159-A1 NON-PEPTIDE OPIOID RECEPTOR MODULATORS VIRGINIA COMMONWEALTH UNIVERSITY (US) 2020-02-27 WO disclosed
US-7307173-B1 Pyrroline chromophores UNIVERSITY OF WASHINGTON (US) 2007-12-11 US disclosed