Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490151 | 0.94 | ELANE (0.62) | ELANE | |
| SCHEMBL4131190 | 0.93 | ELANE (0.68) | ELANEMAPT | |
| SCHEMBL5493300 | 0.88 | ELANE (0.63) | ELANE | |
| SCHEMBL4124431 | 0.86 | ELANE (0.72) | ELANE | |
| SCHEMBL4139009 | 0.85 | ELANE (0.77) | ELANE | |
| SCHEMBL4131024 | 0.85 | ELANE (0.63) | ELANE | |
| SCHEMBL4132323 | 0.85 | ELANE (0.71) | ELANE | |
| SCHEMBL4125991 | 0.84 | ELANE (0.62) | ELANE | |
| SCHEMBL4143355 | 0.84 | ELANE (0.75) | ELANE | |
| SCHEMBL4132216 | 0.83 | ELANE (0.73) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861371-A1 | NOVEL COMPOUNDS II 2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE. | AstraZeneca AB (SE) | 2007-12-05 | — | — | EP | claimed |
| WO-2006098684-A1 | NOVEL COMPOUNDS II 2-PYRIDINE DERIVATIVES AS INHIBITORS OF NEUTROPHILE ELASTASE. | ASTRAZENECA AB (SE) | 2006-09-21 | — | — | WO | claimed |