SCHEMBL5496739

SCHEMBL5496739

CC(N)(C(=O)O)n1cccc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 4/20 0.34
CYP1A2 P05177 3/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GRM2 Q14416 1/20 0.33
CYP2D6 P10635 2/20 0.32
HIF1A Q16665 3/20 0.32
KMT2A Q03164 2/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
GGT1 P19440 1/20 0.30
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21747403 0.77 TSHR (0.38) CYP2C19TSHRALDH1A1CYP2D6HIF1A
SCHEMBL6550536 0.73 TBXAS1 (0.51) ALDH1A1
SCHEMBL1132885 0.71 TBXA2R (0.44) CYP2C19TSHRALDH1A1CYP2D6HIF1A
SCHEMBL29138740 0.70 MAPT (0.38) KMT2AMAPT
SCHEMBL8772696 0.68
SCHEMBL16719687 0.68
SCHEMBL23779750 0.64
SCHEMBL16432395 0.64
SCHEMBL16432394 0.64
SCHEMBL27614610 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1399577-B1 METHOD FOR PRODUCING L-AMINO ACIDS SHOWA DENKO KK (JP) 2007-02-07 EP disclosed
US-20040248118-A1 Method for producing l-amino acids SHOWA DENKO K.K. (JP) 2004-12-09 US disclosed
EP-1399577-A1 METHOD FOR PRODUCING L-AMINO ACIDS Showa Denko K.K. (JP) 2004-03-24 EP disclosed
WO-2003000915-A1 METHOD FOR PRODUCING L-AMINO ACIDS SHOWA DENKO K.K. (JP) 2003-01-03 WO disclosed