Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355916 | 1.00 | MAPT (0.35) | MAPTSLC7A5DPP4DPP8DPP7 | |
| SCHEMBL354706 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP7 | |
| SCHEMBL353690 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP7 | |
| SCHEMBL1445688 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5079153 | 0.82 | DPP4 (0.40) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5706355 | 0.82 | DPP4 (0.40) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL27529254 | 0.82 | DPP4 (0.40) | DPP4DPP8DPP7 | |
| SCHEMBL25430553 | 0.79 | MAPT (0.46) | MAPT | |
| SCHEMBL5493822 | 0.77 | DPP4 (0.33) | DPP4 | |
| Fumaric Acid SCHEMBL4948911 | 0.77 | DPP4 (0.36) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166579-B2 | Prodrugs of DP IV-inhibitors | PROSIDION LIMITED (GB) | 2007-01-23 | — | — | US | claimed |
| US-20050203030-A1 | Novel effectors of dipeptidyl peptidase IV | PROSIDION LIMITED (GB) | 2005-09-15 | — | — | US | claimed |
| CN-1636593-A | Novel effectors of dipeptidyl peptidase IV | PROSIDION LTD (GB) | 2005-07-13 | — | — | CN | claimed |
| US-6890905-B2 | Methods for improving islet signaling in diabetes mellitus and for its prevention | PROSIDION LIMITED (GB) | 2005-05-10 | — | — | US | claimed |
| CN-100348189-C | Combination of a DPP-IV inhibitor and a PPAR-alpha compound | NOVARTIS AG (CH) | 2007-11-14 | — | — | CN | disclosed |
| CN-101035536-A | Combinations of organic compounds | NOVARTIS AG (CH) | 2007-09-12 | — | — | CN | disclosed |
| CN-1901938-A | Combination of a DPP-IV inhibitor and an anti-obesity or appetite regulating agent | NOVARTIS AG (CH) | 2007-01-24 | — | — | CN | disclosed |
| CN-1720042-A | Combination of an dpp-iv inhibitor and a ppar-alpha compound | NOVARTIS AG (CH) | 2006-01-11 | — | — | CN | disclosed |