Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447201 | 0.80 | USP2 (0.40) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL2284853 | 0.80 | USP2 (0.40) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL2094040 | 0.80 | USP2 (0.40) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL1287846 | 0.78 | USP2 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL3730156 | 0.77 | USP2 (0.37) | USP2ALDH1A1LMNACYP1A2TSHR | |
| Cyclohexane SCHEMBL9536108 | 0.77 | CYP2C19 (0.58) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL3345554 | 0.77 | CYP2C19 (0.58) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL6158201 | 0.75 | CYP2C19 (0.54) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL30361807 | 0.73 | USP2 (0.37) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL7387755 | 0.69 | CYP1A2 (0.42) | USP2ALDH1A1LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3958879-A1 | COMPOSITIONS AND METHODS OF IMMUNODEPLETION FOR THE TREATMENT OF MALIGNANT AND NON-MALIGNANT HEMATOLOGICAL DISEASES | Actinium Pharmaceuticals, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
| WO-2020219861-A1 | COMPOSITIONS AND METHODS OF IMMUNODEPLETION FOR THE TREATMENT OF MALIGNANT AND NON-MALIGNANT HEMATOLOGICAL DISEASES | ACTINIUM PHARMACEUTICALS, INC. (US) | 2020-10-29 | — | — | WO | disclosed |
| EP-1412471-A4 | APPARATUS AND METHOD FOR DETERMINING THE ONSET AND PRESENCE OF SEPSIS CONDITIONS | WEBBER ROBERT (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1412471-A1 | APPARATUS AND METHOD FOR DETERMINING THE ONSET AND PRESENCE OF SEPSIS CONDITIONS | Webber, Robert (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003012026-A1 | APPARATUS AND METHOD FOR DETERMINING THE ONSET AND PRESENCE OF SEPSIS CONDITIONS | WEBBER ROBERT (US) | 2003-02-13 | — | — | WO | disclosed |
| EP-0436005-A1 | LABELED POLYPEPTIDE DERIVATIVES. | SANDOZ LTD (CH) | 1991-07-10 | — | — | EP | disclosed |