SCHEMBL1287846

SCHEMBL1287846

O=C(O)CC1(CC(=O)O)CCCCCCNNNNC1(CC(=O)O)CC(=O)O.[Gd]

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
CYP1A2 P05177 1/20 0.39
TSHR P16473 1/20 0.39
BLM P54132 1/20 0.39
CACNA2D1 P54289 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16447201 0.98 USP2 (0.40) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL2094040 0.98 USP2 (0.40) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL2284853 0.98 USP2 (0.40) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL3730156 0.97 USP2 (0.37) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL30361807 0.93 USP2 (0.37) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL28609548 0.85 USP2 (0.31) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL29198910 0.82
SCHEMBL5497063 0.78 USP2 (0.44) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL29973085 0.71 CYP2C19 (0.42) USP2ALDH1A1LMNACYP1A2TSHR
SCHEMBL3345554 0.71 CYP2C19 (0.58) USP2ALDH1A1LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1861043-B1 DEVICE AND SYSTEM FOR AIDING VALVE ANNULOPLASTY MEDTRONIC VASCULAR INC (US) 2019-08-07 EP claimed
US-9101669-B2 Self-assembed conjugate and use thereof POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2015-08-11 US claimed
US-20130195751-A1 SELF-ASSEMBED CONJUGATE AND USE THEREOF POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2013-08-01 US claimed
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES NATIONAL INSTITUTES OF HEALTH (US) 2013-05-30 US claimed
EP-2552458-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES Wayne State University (US) 2013-02-06 EP claimed
WO-2011123591-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES WAYNE STATE UNIVERSITY (US) 2011-10-06 WO claimed
US-7955385-B2 Device, system, and method for aiding valve annuloplasty MEDTRONIC VASCULAR, INC. (US) 2011-06-07 US claimed
EP-1861043-A1 DEVICE, SYSTEM, AND METHOD FOR AIDING VALVE ANNULOPLASTY Medtronic Vascular, Inc. (US) 2007-12-05 EP claimed
US-20070238979-A1 Reference Devices for Placement in Heart Structures for Visualization During Heart Valve Procedures MEDTRONIC VASCULAR, INC. (US) 2007-10-11 US claimed
WO-2006093656-A1 DEVICE, SYSTEM, AND METHOD FOR AIDING VALVE ANNULOPLASTY MEDTRONIC VASCULAR, INC. (US) 2006-09-08 WO claimed
US-20060195134-A1 Device, system, and method for aiding valve annuloplasty MEDTRONIC VASCULAR, INC. (US) 2006-08-31 US claimed
EP-3998336-B1 MICROORGANISMS AND METHODS FOR PRODUCING CANNABINOIDS AND CANNABINOID DERIVATIVES UNIV CALIFORNIA (US) 2026-01-07 EP disclosed
US-12460185-B2 Optimized cannabinoid synthase polypeptides DEMETRIX, INC. (US) 2025-11-04 US disclosed
US-12215327-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-04 US disclosed
US-12048710-B2 Compositions and methods for modification of biomolecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-30 US disclosed
EP-1812031-A2 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-08-01 EP disclosed
WO-2006093656-A1 DEVICE, SYSTEM, AND METHOD FOR AIDING VALVE ANNULOPLASTY MEDTRONIC VASCULAR, INC. (US) 2006-09-08 WO disclosed
US-20060195134-A1 Device, system, and method for aiding valve annuloplasty MEDTRONIC VASCULAR, INC. (US) 2006-08-31 US disclosed
US-20060110782-A1 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-25 US disclosed
WO-2006050262-A2 COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12048710-B2 Compositions and methods for modification of biomolecules PTMS, QPCT, ANPEP USP2 2277/4885ALDH1A1 3718/4885LMNA 1871/4885
US-12215327-B2 Microorganisms and methods for producing cannabinoids and cannabinoid derivatives CNR2, CNR1, FAAH USP2 2485/4885ALDH1A1 2306/4885LMNA 4339/4885
US-20130136697-A1 INJECTABLE DENDRIMER HYDROGEL NANOPARTICLES UACA, PAM, JAK3 USP2 864/4885ALDH1A1 1369/4885LMNA 3370/4885
US-20060110782-A1 cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling PTMS, QPCT, DNPEP USP2 2504/4885ALDH1A1 3269/4885LMNA 3610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.