Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383677 | 0.99 | CDK1 (0.70) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| SCHEMBL14567055 | 0.99 | CDK1 (0.70) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| SCHEMBL446310 | 0.99 | CDK1 (0.70) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| SCHEMBL2330852 | 0.97 | CDK1 (0.68) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| SCHEMBL4622847 | 0.97 | CDK1 (0.72) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| Trimethylammonium SCHEMBL29036046 | 0.94 | CDK1 (0.64) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| Alcohol SCHEMBL1277192 | 0.94 | CDK1 (0.67) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| SCHEMBL2330956 | 0.93 | CDK1 (0.74) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| Alcohol SCHEMBL2337118 | 0.92 | CDK1 (0.66) | CDK1TDP1MAPK1NAAAKCNMA1 | |
| Pyrrole SCHEMBL30481042 | 0.91 | CDK1 (0.61) | CDK1TDP1MAPK1NAAAKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232524-A1 | Oral administration of calcitonin | NOVARTIS AG (CH) | 2007-10-04 | — | — | US | claimed |
| US-20060135402-A1 | Oral administration of calcitonin | AZRIA MOISE | 2006-06-22 | — | — | US | claimed |
| EP-1526871-A1 | ORAL ADMINISTRATION OF CALCITONIN | Novartis AG (CH) | 2005-05-04 | — | — | EP | claimed |
| WO-2004012772-A1 | ORAL ADMINISTRATION OF CALCITONIN | NOVARTIS AG (CH) | 2004-02-12 | — | — | WO | claimed |