SCHEMBL446310

SCHEMBL446310

O=C(O)CCCCCCCNC(=O)c1cc(Cl)ccc1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.70
TDP1 Q9NUW8 1/20 0.62
MAPK1 P28482 1/20 0.55
NAAA Q02083 1/20 0.53
KCNMA1 Q12791 1/20 0.52
FABP4 P15090 1/20 0.51
TMPRSS4 Q9NRS4 2/20 0.50
PTGS1 P23219 1/20 0.49
P2RX1 P51575 3/20 0.49
P2RX4 Q99571 1/20 0.49
P2RX7 Q99572 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA12 O43570 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29383677 1.00 CDK1 (0.70) CDK1TDP1MAPK1NAAAKCNMA1
SCHEMBL14567055 1.00 CDK1 (0.70) CDK1TDP1MAPK1NAAAKCNMA1
SCHEMBL2330852 0.99 CDK1 (0.68) CDK1TDP1MAPK1NAAAKCNMA1
SCHEMBL5497301 0.99 CDK1 (0.68) CDK1TDP1MAPK1NAAAKCNMA1
SCHEMBL4622847 0.99 CDK1 (0.72) CDK1TDP1MAPK1NAAAKCNMA1
Trimethylammonium SCHEMBL29036046 0.95 CDK1 (0.64) CDK1TDP1MAPK1NAAAKCNMA1
Alcohol SCHEMBL1277192 0.95 CDK1 (0.67) CDK1TDP1MAPK1NAAAKCNMA1
SCHEMBL2330956 0.94 CDK1 (0.74) CDK1TDP1MAPK1NAAAKCNMA1
Alcohol SCHEMBL2337118 0.94 CDK1 (0.66) CDK1TDP1MAPK1NAAAKCNMA1
Pyrrole SCHEMBL30481042 0.93 CDK1 (0.61) CDK1TDP1MAPK1NAAAKCNMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 930 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069697-A1 METHOD OF TREATING CANCER INTENSITY THERAPEUTICS INC (US) 2026-03-12 US claimed
US-20260071218-A1 Oral Delivery of Antisense Conjugates Targeting PCSK9 CIVI BIOPHARMA INC (US) 2026-03-12 US claimed
US-20260000617-A1 ORAL BIOLOGIC MACROMOLECULE DELIVERY SYSTEM NUTRITION & BIOSCIENCES USA 1 LLC (US) 2026-01-01 US claimed
EP-4642440-A1 COMPOSITIONS AND METHODS TO INCREASE THE SYSTEMIC BIOAVAILABILITY OF A POLYPEPTIDE THERAPEUTIC AGENT UNDERGOING ORAL ADMINISTRATION ALGIPHARMA AS (NO) 2025-11-05 EP claimed
EP-4611730-A1 ORAL BIOLOGIC MACROMOLECULE DELIVERY SYSTEM Nutrition & Biosciences USA 1, LLC (US) 2025-09-10 EP claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
WO-2025097068-A1 ORAL DOSAGE FORM WITH IONICALLY CHARGEABLE HYDROGEL FOR DELIVERY OF ACTIVE AGENT AND PERMEATION ENHANCER ENTREGA INC. (US) 2025-05-08 WO claimed
US-12291708-B2 Oral delivery of antisense conjugates targeting PCSK9 CIVI BIOPHARMA, INC. (US) 2025-05-06 US claimed
US-20250009666-A1 RAPIDLY DISSOLVING SALT TABLET COMPOSITIONS AND METHODS TARRATS LUISAM (US) 2025-01-09 US claimed
US-20240261411-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS SYNTIS BIO, INC. 2024-08-08 US claimed
EP-1420827-A1 5-CNAC AS ORAL DELIVERY AGENT FOR PARATHYROID HORMONE FRAGMENTS Novartis AG (CH) 2004-05-26 EP claimed
WO-2004012772-A1 ORAL ADMINISTRATION OF CALCITONIN NOVARTIS AG (CH) 2004-02-12 WO claimed
WO-2004006907-A1 MODIFIED AMINO ACID FOR THE INHIBITION OF PLATELET AGGREGATION NOVARTIS AG (CH) 2004-01-22 WO claimed
US-20030216593-A1 Method of preparing salicylamides NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2003-11-20 US claimed
WO-2003015822-A1 5-CNAC AS ORAL DELIVERY AGENT FOR PARATHYROID HORMONE FRAGMENTS NOVARTIS AG (CH) 2003-02-27 WO claimed
EP-1175390-A4 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES EMISPHERE TECH INC (US) 2002-09-04 EP claimed
US-20020065255-A1 Disodium salts, monohydrates, and ethanol solvates for delivering active agents EMISPHERE TECHNOLOGIES, INC. (US) 2002-05-30 US claimed
EP-1175390-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES Emisphere Technologies, Inc. (US) 2002-01-30 EP claimed
WO-2001092206-A1 METHOD OF PREPARING SALICYLAMIDES EMISPHERE TECHNOLOGIES, INC. (US) 2001-12-06 WO claimed
WO-2000059863-A1 DISODIUM SALTS, MONOHYDRATES, AND ETHANOL SOLVATES EMISPHERE TECHNOLOGIES, INC. (US) 2000-10-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065255-A1 Disodium salts, monohydrates, and ethanol solvates for delivering active agents ADH1C, CLIC1, SLC9A1 CDK1 4120/4885TDP1 4270/4885MAPK1 2874/4885
US-20240261411-A1 PERMEATION ENHANCERS FOR GASTROINTESTINAL SYNTHETIC EPITHELIAL LININGS FABP2, SLC10A2, FABP6 CDK1 2604/4885TDP1 4613/4885MAPK1 3260/4885
US-20260071218-A1 Oral Delivery of Antisense Conjugates Targeting PCSK9 PCSK9, ALPI, SLC10A2 CDK1 3743/4885TDP1 2676/4885MAPK1 2860/4885
US-20030216593-A1 Method of preparing salicylamides SCLY, ADSL, SIK3 CDK1 880/4885TDP1 3446/4885MAPK1 2978/4885
US-12291708-B2 Oral delivery of antisense conjugates targeting PCSK9 PCSK9, SCD5, PCSK7 CDK1 2420/4885TDP1 1921/4885MAPK1 4221/4885
US-20260000617-A1 ORAL BIOLOGIC MACROMOLECULE DELIVERY SYSTEM SI, FABP2, VIP CDK1 3764/4885TDP1 4084/4885MAPK1 2339/4885
US-20260069697-A1 METHOD OF TREATING CANCER PBK, GZMB, KLRK1 CDK1 3686/4885TDP1 3626/4885MAPK1 4256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.