SCHEMBL5497627

SCHEMBL5497627

C=CCNC(=O)OCC=C

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
MAPT P10636 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
KMT2A Q03164 2/20 0.42
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.39
ALDH1A1 P00352 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CASP1 P29466 2/20 0.38
FAAH O00519 1/20 0.37
PKM P14618 1/20 0.37
RAB9A P51151 1/20 0.36
HPGD P15428 1/20 0.35
ERN1 O75460 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12443703 0.87 MEN1 (0.39) TSHRMAPTSMN1; SMN2KMT2ACACNA1B
SCHEMBL27605571 0.87 SMN1; SMN2 (0.42) TSHRMAPTSMN1; SMN2KMT2ACACNA1B
SCHEMBL4746818 0.84 SMN1; SMN2 (0.46) TSHRMAPTSMN1; SMN2KMT2AMEN1
SCHEMBL9486696 0.84 MAPT (0.42) TSHRMAPTSMN1; SMN2KMT2ACACNA1B
SCHEMBL13055388 0.84 MAPT (0.42) TSHRMAPTKMT2ACACNA1BAPBA1
SCHEMBL23111386 0.84 TSHR (0.46) TSHRMAPTSMN1; SMN2KMT2AALDH1A1
SCHEMBL8577434 0.84 MEN1 (0.37) TSHRMAPTSMN1; SMN2KMT2ACACNA1B
SCHEMBL9641049 0.82
SCHEMBL3112108 0.82
SCHEMBL248893 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3034526-B1 Cover net systems for encapsulation films EVONIK DEGUSSA GMBH (DE) 2017-06-14 EP claimed
CN-104017234-B A kind of polyurethane sponge-double carbamate class compound oil spilling administers the preparation method of material HARBIN INSTITUTE OF TECHNOLOGY (CN) 2016-04-20 CN claimed
US-20140316075-A1 Linear Silicone Block Copolymer and Method of Making the Same WANG XIAOHUA (CN) 2014-10-23 US claimed
CN-104017234-A Preparation method of polyurethane sponge and dicarbamic alkyl ester oil gelling agent composite oil spillage treatment material HARBIN INST OF TECHNOLOGY 2014-09-03 CN claimed
EP-2756022-A1 LINEAR SILICONE BLOCK COPOLYMER AND METHOD OF MAKING THE SAME Dow Global Technologies LLC (US) 2014-07-23 EP claimed
WO-2013071501-A1 LINEAR SILICONE BLOCK COPOLYMER AND METHOD OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2013-05-23 WO claimed
WO-2000005200-A1 SUBSTITUTED N-ALYKL-O-ALKYL CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 2000-02-03 WO claimed
EP-0234971-B1 SUBSTITUTED AMIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM RHONE-POULENC SANTE (FR) 1990-09-05 EP claimed
US-4753933-A ANXIOLYTIS, ANTIEPILEPTICS, MUSCLE RELAXANTS RHONE-POULENC SANTE (FR) 1988-06-28 US claimed
US-4243462-A LAMINATION, POLYMERS, FREE RADICAL CATALYST NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-01-06 US claimed
CN-110382560-A Crystalline radical polymerizable composition for electric/electronic component, electric/electronic component molded body using the same, and method for producing the electric/electronic component molded body 日本优必佳株式会社 2019-10-25 CN disclosed
WO-2018028365-A1 DYNAMIC POLYMER WITH HYBRID CROSS-LINKED NETWORK AND APPLICATION THEREOF 翁秋梅 2018-02-15 WO disclosed
EP-3034526-B1 Cover net systems for encapsulation films EVONIK DEGUSSA GMBH (DE) 2017-06-14 EP disclosed
US-20170037282-A1 ADHESIVES COMPRISING (METH)ALLYL CROSSLINKER AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-02-09 US disclosed
US-20170037282-A1 ADHESIVES COMPRISING (METH)ALLYL CROSSLINKER AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-02-09 US disclosed
US-4279897-A INSECTICIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1981-07-21 US disclosed
US-4243462-A LAMINATION, POLYMERS, FREE RADICAL CATALYST NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-01-06 US disclosed
EP-0015749-A1 Phosphoramidothioates, process for preparing them and insecticidal compositions containing them THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1980-09-17 EP disclosed
US-4196289-A REACTING AN ALLYL HALIDE AND AN ALKALI CYANATE NIPPON KASEI CHEMICAL CO., LTD. (JP) 1980-04-01 US disclosed
US-4091157-A UNSATURATED POLYMER LAYER, FREE RADICAL INITIATOR LAYER NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) 1978-05-23 US disclosed