Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812049 | 0.90 | KIF11 (0.60) | KIF11ALDH1A1KDM4EAHRMAPT | |
| SCHEMBL869229 | 0.89 | AHR (0.53) | KIF11ALDH1A1KDM4EAHRMAPT | |
| SCHEMBL29213721 | 0.82 | KIF11 (0.64) | KIF11ALDH1A1KDM4EAHRGPR3 | |
| SCHEMBL2312163 | 0.82 | KIF11 (0.64) | KIF11ALDH1A1KDM4EAHRGPR3 | |
| SCHEMBL6009616 | 0.82 | KIF11 (0.74) | KIF11ALDH1A1KDM4EAHRMAPT | |
| SCHEMBL13484452 | 0.80 | GAA (0.56) | KIF11ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28521664 | 0.79 | KIF11 (0.70) | KIF11ALDH1A1KDM4EAHRGPR3 | |
| SCHEMBL7812608 | 0.78 | KIF11 (0.58) | KIF11ALDH1A1KDM4EAHRGPR3 | |
| SCHEMBL11296266 | 0.78 | KIF11 (0.68) | KIF11ALDH1A1KDM4EAHRGPR3 | |
| SCHEMBL278610 | 0.78 | KIF11 (1.00) | KIF11ALDH1A1KDM4EAHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689435-A4 | ANTI-THYMOCYTE ANTISERUM AND USE THEREOF TO TRIGGER B CELL APOPTOSIS | UNIV ROCHESTER (US) | 2007-10-03 | — | — | EP | disclosed |
| US-20070031406-A1 | Anti-thymocyte antiserum and use thereof to trigger b cell apoptosis | UNIVERSITY OF ROCHESTER | 2007-02-08 | — | — | US | disclosed |
| EP-1689435-A1 | ANTI-THYMOCYTE ANTISERUM AND USE THEREOF TO TRIGGER B CELL APOPTOSIS | University of Rochester (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005042019-A1 | ANTI-THYMOCYTE ANTISERUM AND USE THEREOF TO TRIGGER B CELL APOPTOSIS | UNIVERSITY OF ROCHESTER (US) | 2005-05-12 | — | — | WO | disclosed |