Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5497952 | 0.87 | FOLH1 (0.59) | FOLH1 | |
| SCHEMBL11651627 | 0.86 | KMT2A (0.50) | KMT2AFOLH1CA2CA1MMP2 | |
| SCHEMBL11651630 | 0.86 | KMT2A (0.50) | KMT2AFOLH1CA2CA1MMP2 | |
| SCHEMBL7711811 | 0.86 | KMT2A (0.50) | KMT2ACA2CA1MMP2MMP9 | |
| SCHEMBL3448329 | 0.85 | KMT2A (0.64) | KMT2AFOLH1CA2CA1MMP2 | |
| SCHEMBL3448327 | 0.85 | KMT2A (0.64) | KMT2AFOLH1CA2CA1MMP2 | |
| SCHEMBL28975404 | 0.85 | KMT2A (0.47) | KMT2AFOLH1CA2CA1MMP2 | |
| SCHEMBL28103437 | 0.84 | KMT2A (0.49) | KMT2AFOLH1CA2CA1MMP2 | |
| Hydrochloric Acid SCHEMBL23834278 | 0.84 | KMT2A (0.62) | KMT2AFOLH1CA2CA1MMP2 | |
| SCHEMBL11037422 | 0.82 | KMT2A (0.47) | KMT2AFOLH1CA2CA1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868535-B9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2007-05-09 | — | — | EP | claimed |
| EP-0868535-B2 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | QIAGEN GENOMICS INC (US) | 2006-01-04 | — | — | EP | claimed |
| EP-0868535-B1 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | RAPIGENE INC (US) | 2000-04-12 | — | — | EP | claimed |