SCHEMBL5497952

SCHEMBL5497952

O=C(O)CCC(Nc1ccc(F)cc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 17/20 0.59
GGH Q92820 1/20 0.48
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497956 0.87 KMT2A (0.49) FOLH1
SCHEMBL60370 0.84 GAA (0.62) FOLH1GGHGAA
SCHEMBL60371 0.84 GAA (0.62) FOLH1GGHGAA
SCHEMBL4828335 0.83 GGH (0.48) FOLH1GGHGAA
SCHEMBL28535426 0.83 GGH (0.48) FOLH1GGHGAA
SCHEMBL11835127 0.83 GGH (0.48) FOLH1GGHGAA
SCHEMBL8127010 0.83 FOLH1 (0.45) FOLH1GAA
SCHEMBL4694182 0.80 HTT (0.48) GAA
SCHEMBL28929153 0.80 GGH (0.44) FOLH1GGHGAA
SCHEMBL5497074 0.80 MAPK14 (0.48) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0868535-B9 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES QIAGEN GENOMICS INC (US) 2007-05-09 EP claimed
EP-0868535-B2 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES QIAGEN GENOMICS INC (US) 2006-01-04 EP claimed
EP-0868535-B1 METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES RAPIGENE INC (US) 2000-04-12 EP claimed