Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.51 |
| ▸ | FAP | Q12884 | 17/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.51 |
| ▸ | PREP | P48147 | 8/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498101 | 1.00 | DPP4 (0.51) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL2956816 | 0.80 | FAP (0.59) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL2959334 | 0.80 | FAP (0.59) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL2956815 | 0.78 | FAP (0.54) | DPP4FAPDPP8DPP9PREP | |
| SCHEMBL2555618 | 0.73 | SLC6A4 (0.47) | — | |
| SCHEMBL20905448 | 0.73 | SLC6A4 (0.47) | — | |
| SCHEMBL4853479 | 0.73 | SLC6A4 (0.47) | — | |
| SCHEMBL25105353 | 0.71 | SLC6A2 (0.48) | — | |
| SCHEMBL25105977 | 0.71 | SLC6A2 (0.48) | — | |
| SCHEMBL25260214 | 0.71 | SLC6A2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1689757-A4 | HETEROCYCLIC BORONIC ACID COMPOUNDS | PHENOMIX CORP (US) | 2007-01-10 | — | — | EP | disclosed |
| EP-1689757-A1 | HETEROCYCLIC BORONIC ACID COMPOUNDS | Phenomix Corporation (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005047297-A1 | HETEROCYCLIC BORONIC ACID COMPOUNDS | PHENOMIX CORPORATION (US) | 2005-05-26 | — | — | WO | disclosed |