Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.39 |
| ▸ | ESRRA | P11474 | 2/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168094 | 0.89 | AR (0.56) | ARPGRNR3C1NR3C2SLC22A12 | |
| SCHEMBL5502088 | 0.86 | AR (0.59) | ARPGRNR3C1NR3C2SLC22A12 | |
| SCHEMBL4179470 | 0.85 | AR (0.63) | ARPGRNR3C1NR3C2SLC22A12 | |
| SCHEMBL4182930 | 0.80 | AR (0.62) | ARESRRAMRGPRX4SLC6A4SLC6A3 | |
| SCHEMBL4188051 | 0.79 | AR (0.56) | ARSLC22A12ESRRAMRGPRX4SLC6A4 | |
| SCHEMBL4183157 | 0.77 | AR (0.73) | ARSLC22A12ESRRAMRGPRX4SLC6A4 | |
| SCHEMBL4183156 | 0.77 | AR (0.68) | ARSLC22A12ESRRAMRGPRX4SLC6A4 | |
| SCHEMBL23409847 | 0.75 | MRGPRX4 (0.47) | ARSLC22A12ESRRAESRRBESR1 | |
| SCHEMBL29788295 | 0.75 | MRGPRX4 (0.47) | ARSLC22A12ESRRAESRRBESR1 | |
| SCHEMBL4175734 | 0.73 | AR (0.59) | ARPGRNR3C1NR3C2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781280-A2 | ANDROGEN MODULATORS | Warner-Lambert Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018723-A2 | ANDROGEN MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2006-02-23 | — | — | WO | disclosed |