Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 8/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670836 | 0.83 | AHR (0.59) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL689189 | 0.81 | AHR (0.50) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL5728887 | 0.81 | AHR (0.54) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL1460158 | 0.79 | AHR (0.49) | AHRMAOBHTR1ASLC6A2SLC6A4 | |
| SCHEMBL4889909 | 0.79 | AHR (0.53) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL9050921 | 0.79 | AHR (0.49) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL9050907 | 0.78 | AHR (0.47) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL5506894 | 0.78 | GRIA1 (0.34) | PGRMAOBHTR1ADRD2HTR2A | |
| SCHEMBL4404868 | 0.77 | AHR (0.57) | PGRAHRMAOBHTR1ASLC6A2 | |
| SCHEMBL260866 | 0.77 | AHR (0.53) | PGRAHRMAOBHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781642-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006016221-A1 | OXAZOLIDINONES CONTAINING OXINDOLES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-02-16 | — | — | WO | disclosed |