Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28657406 | 0.81 | PRSS1 (0.58) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL11574577 | 0.76 | CA1 (0.47) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL4130950 | 0.73 | SRC (0.41) | CYP2C19TSHRF2SRCALDH1A1 | |
| SCHEMBL30207547 | 0.73 | CA1 (0.44) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL6916245 | 0.73 | CA1 (0.44) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL750558 | 0.72 | CA2 (0.52) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL3252117 | 0.72 | CA1 (0.52) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL3626579 | 0.72 | CA2 (0.52) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL5671478 | 0.72 | PRSS1 (0.52) | PRSS1PRSS2PRSS3FAAHELANE | |
| SCHEMBL18189420 | 0.72 | EPHX1 (0.51) | PRSS1PRSS2PRSS3FAAHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166568-B1 | Compositions and methods to inhibit formation of the C5b-9 complex of complement | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 2007-01-23 | — | — | US | disclosed |
| US-20030166565-A1 | Compositions and methods to inhibit formation of the C5b-9 complex of complement | OKLAHOMA MEDICAL RESEARCH FOUNDATION | 2003-09-04 | — | — | US | disclosed |
| EP-1053254-A2 | COMPOSITIONS AND METHODS TO INHIBIT FORMATION OF THE C5b-9 COMPLEX OF COMPLEMENT | Oklahoma Medical Research Foundation (US) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040115-A9 | COMPOSITIONS AND METHODS TO INHIBIT FORMATION OF THE C5b-9 COMPLEX OF COMPLEMENT | OKLAHOMA MED RES FOUND (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999040115-A2 | COMPOSITIONS AND METHODS TO INHIBIT FORMATION OF THE C5b-9 COMPLEX OF COMPLEMENT | OKLAHOMA MEDICAL RESEARCH FOUNDATION (US) | 1999-08-12 | — | — | WO | disclosed |
| US-5859339-A | HYBRIDIZED POLYNUCLEOTIDES COMPRISING A PROMOTER SEQUENCE GREATER THAN ABOUT FIFTY NUCLEOTIDES LINKED TO A HETEROLOGOUS POLYNUCLEOTIDE SEQUENCE USED TO PRODUCE TRANSGENIC PLANTS RESISTANT TO THE PATHOGEN. | THE REAGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0805860-A2 | PROCEDURES AND MATERIALS FOR CONFERRING DISEASE RESISTANCE IN PLANTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022375-A2 | PROCEDURES AND MATERIALS FOR CONFERRING DISEASE RESISTANCE IN PLANTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-07-25 | — | — | WO | disclosed |