Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | IKBKB | O14920 | 6/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | ITK | Q08881 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.34 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL946096 | 0.99 | ADORA1 (0.47) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL27663322 | 0.90 | ADORA1 (0.58) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL27663397 | 0.87 | ADORA1 (0.53) | ADORA1ADORA2AIKBKBADORA3CHUK | |
| SCHEMBL950112 | 0.87 | ADORA1 (0.46) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL945957 | 0.85 | ADORA1 (0.45) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL3737757 | 0.85 | ADORA1 (0.45) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL945816 | 0.85 | ADORA1 (0.45) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL28761086 | 0.85 | ADORA1 (0.52) | ADORA1ADORA2AIKBKBADORA3CHUK | |
| SCHEMBL27663484 | 0.85 | ADORA1 (0.46) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL3740316 | 0.84 | ADORA1 (0.44) | ADORA1ADORA2AIKBKBADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740574-B1 | 4-AMINO-5-CYANOPYRIMIDINE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2007-06-27 | — | — | EP | disclosed |