Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | IKBKB | O14920 | 12/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CHUK | O15111 | 2/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | PASK | Q96RG2 | 1/20 | 0.33 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3740316 | 0.99 | ADORA1 (0.44) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL5499490 | 0.85 | ADORA1 (0.47) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL945819 | 0.84 | ADORA1 (0.62) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL946096 | 0.84 | ADORA1 (0.47) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL3740320 | 0.84 | ADORA1 (0.61) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL950112 | 0.84 | ADORA1 (0.46) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL3737757 | 0.83 | ADORA1 (0.45) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL945957 | 0.83 | ADORA1 (0.45) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL27663322 | 0.83 | ADORA1 (0.58) | ADORA1ADORA2AIKBKBADORA3ADORA2B | |
| SCHEMBL3743152 | 0.82 | ADORA1 (0.45) | ADORA1ADORA2AIKBKBADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989446-B2 | 4-amino 5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-08-02 | — | — | US | claimed |
| US-20110009620-A1 | 4-Amino-5-cyanopyrimidine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. | 2011-01-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009620-A1 | 4-Amino-5-cyanopyrimidine derivatives | ADORA2A, ADORA1, ADORA3 | ADORA1 2/4885ADORA2A 1/4885IKBKB 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.