Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7867544 | 0.96 | CA1 (0.57) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL1968616 | 0.96 | CA1 (0.57) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL9729939 | 0.93 | CA1 (0.53) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL12465625 | 0.92 | CA1 (0.61) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL12484395 | 0.92 | — | — | |
| Acetic Acid SCHEMBL7517431 | 0.92 | — | — | |
| Acetic Acid SCHEMBL17312004 | 0.92 | CA1 (0.61) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL11660792 | 0.92 | CA1 (0.61) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL7593550 | 0.92 | CA1 (0.61) | CA1CA4MEN1KMT2ACA5A | |
| Acetic Acid SCHEMBL6403805 | 0.92 | CA1 (0.61) | CA1CA4MEN1KMT2ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196234-B1 | CATALYST SYSTEM FOR TREATING DIESEL ENGINE EXHAUST GASES AND METHOD | ENGELHARD CORP (US) | 2007-04-18 | — | — | EP | disclosed |
| US-7078004-B2 | Diesel oxidation catalyst | ENGELHARD CORPORATION (US) | 2006-07-18 | — | — | US | disclosed |
| US-20030108465-A1 | Diesel oxidation catalyst | ENGELHARD CORPORATION | 2003-06-12 | — | — | US | disclosed |
| EP-1196234-A1 | OXIDATION CATALYST FOR TREATING DIESEL ENGINE EXHAUST GASES | Engelhard Corporation (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002083-A1 | OXIDATION CATALYST FOR TREATING DIESEL ENGINE EXHAUST GASES | ENGELHARD CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |