Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5499994 | 0.93 | CA1 (0.61) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL7867544 | 0.90 | CA1 (0.57) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL1968616 | 0.90 | CA1 (0.57) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL12465625 | 0.86 | CA1 (0.61) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL11660792 | 0.86 | CA1 (0.61) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL7517431 | 0.86 | — | — | |
| Acetic Acid SCHEMBL12484395 | 0.86 | — | — | |
| Acetic Acid SCHEMBL17312004 | 0.86 | CA1 (0.61) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL6403805 | 0.86 | CA1 (0.61) | CA1CA4MEN1KMT2AMAPK1 | |
| Acetic Acid SCHEMBL7593550 | 0.86 | CA1 (0.61) | CA1CA4MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147842-A | Multilayer on monolithic support; platinum group metal, activated aluminum, and(or) cerium, zirconium oxide | N.E. CHEMCAT CORPORATION (JP) | 1992-09-15 | — | — | US | disclosed |