Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665425 | 0.90 | ALDH1A1 (0.60) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL951563 | 0.90 | ALDH1A1 (0.60) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL2917719 | 0.87 | ALDH1A1 (0.66) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL29038407 | 0.87 | ALDH1A1 (0.66) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL4713598 | 0.87 | ALDH1A1 (0.66) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL19922403 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL309700 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL7429520 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL17627748 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNACYP19A1 | |
| SCHEMBL17035687 | 0.86 | ALDH1A1 (0.64) | ALDH1A1LMNACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638677-A4 | CATALYTIC ASYMMETRIC DESYMMETRIZATION OF PROCHIRAL AND MESO CYCLIC ANHYDRIDES | UNIV BRANDEIS (US) | 2007-10-10 | — | — | EP | disclosed |
| EP-1638677-A2 | CATALYTIC ASYMMETRIC DESYMMETRIZATION OF PROCHIRAL AND MESO CYCLIC ANHYDRIDES | Brandeis University (US) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110609-A2 | CATALYTIC ASYMMETRIC DESYMMETRIZATION OF PROCHIRAL AND MESO CYCLIC ANHYDRIDES | BRANDEIS UNIVERSITY (US) | 2004-12-23 | — | — | WO | disclosed |
| EP-0093084-B1 | 1-CARBOXYALKANOYLINDOLINE-2-CARBOXYLIC-ACID ESTERS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTIC USE | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |
| EP-0097127-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1983-12-28 | — | — | EP | disclosed |
| EP-0093084-A1 | 1-Carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |