Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560035 | 0.98 | TLR8 (0.48) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL158196 | 0.98 | TLR8 (0.48) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL20694916 | 0.98 | TLR8 (0.48) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL9065394 | 0.98 | TLR8 (0.48) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL3403921 | 0.98 | TLR8 (0.48) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL6698577 | 0.97 | TLR8 (0.49) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL2200831 | 0.95 | TLR8 (0.47) | TLR8LIPGMAPTCYP3A4MEN1 | |
| SCHEMBL20694968 | 0.86 | TLR8 (0.46) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL20694980 | 0.84 | TLR8 (0.47) | TLR8LIPGKCNH2MAPTCYP3A4 | |
| SCHEMBL6840627 | 0.83 | TLR8 (0.39) | TLR8LIPGKCNH2MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809726-A2 | 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006047011-A2 | 1,3-DITHIOLANE-2-THIONE ADDITIVES FOR LUBRICANTS AND FUELS | CHEMTURA CORPORATION (US) | 2006-05-04 | — | — | WO | disclosed |