SCHEMBL560035

SCHEMBL560035

CCCCCCCCCc1[c]c2ccccc2cc1CCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.48
LIPG Q9Y5X9 1/20 0.44
KCNH2 Q12809 1/20 0.40
MAPT P10636 3/20 0.39
CYP3A4 P08684 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
ALOX5 P09917 1/20 0.39
TYR P14679 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GPR3 P46089 1/20 0.37
NR1H2 P55055 1/20 0.37
NR1H3 Q13133 1/20 0.37
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065394 1.00 TLR8 (0.48) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL3403921 1.00 TLR8 (0.48) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL158196 1.00 TLR8 (0.48) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL20694916 1.00 TLR8 (0.48) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL5500478 0.98 TLR8 (0.47) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL6698577 0.98 TLR8 (0.49) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL2200831 0.93 TLR8 (0.47) TLR8LIPGMAPTCYP3A4MEN1
SCHEMBL20694968 0.88 TLR8 (0.46) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL20694980 0.86 TLR8 (0.47) TLR8LIPGKCNH2MAPTCYP3A4
SCHEMBL6840627 0.84 TLR8 (0.39) TLR8LIPGKCNH2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130216723-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2013-08-22 US claimed
EP-2203519-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS King Industries (US) 2010-07-07 EP claimed
US-20090104363-A1 Sulfonate esters as latent acid catalysts KING INDUSTRIES 2009-04-23 US claimed
WO-2009045466-A1 SULFONATE ESTERS AS LATENT ACID CATALYSTS KING INDUSTRIES (US) 2009-04-09 WO claimed
EP-0377931-B1 Isocyanate modified blocked sulfonic acid ester as a crosslinking catalyst KING INDUSTRIES INC (US) 1993-11-03 EP claimed
EP-0377931-A2 Isocyanate modified blocked sulfonic acid ester as a crosslinking catalyst KING INDUSTRIES, INC. (US) 1990-07-18 EP claimed
EP-0097616-B1 POLYALKYLPIPERIDINE ESTERS OF SULFONIC ACIDS CIBA-GEIGY AG (CH) 1986-08-20 EP claimed
US-4537923-A CURING CATALYSTS FOR ACID-CURABLE RESINS CIBA GEIGY CORPORATION (US) 1985-08-27 US claimed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US claimed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US claimed
EP-0097616-A1 Polyalkylpiperidine esters of sulfonic acids CIBA-GEIGY AG (CH) 1984-01-04 EP claimed
US-20240240095-A1 NEW COMPOSITIONS FOR REDUCING CRYSTALLIZATION OF PARAFFIN CRYSTALS IN FUELS BASF SE (DE) 2024-07-18 US disclosed
WO-2024126076-A1 PROCESS FOR REDUCTION OF ASPHALTENES FROM MARINE FUELS BASF SE (DE) 2024-06-20 WO disclosed
EP-4074810-B1 NEW COMPOSITIONS FOR REDUCING CRYSTALLIZATION OF PARAFFIN CRYSTALS IN FUELS BASF SE (DE) 2023-11-15 EP disclosed
CN-111100227-B Propylene polymerization method and device 中国石油化工股份有限公司 2022-10-21 CN disclosed
US-4537923-A CURING CATALYSTS FOR ACID-CURABLE RESINS CIBA GEIGY CORPORATION (US) 1985-08-27 US disclosed
EP-0139609-A1 Process for curing acid-curable lacquers CIBA-GEIGY AG (CH) 1985-05-02 EP disclosed
US-4477618-A CROSSLINKING AN ACTIVE HYDROGEN-CONTAINING RESIN BLEND BY BAKING; STORAGE STABILITY PPG INDUSTRIES, INC. (US) 1984-10-16 US disclosed
US-4454274-A Aminoplast curable coating compositions containing cycloaliphatic sulfonic acid esters as latent acid catalysts PPG INDUSTRIES, INC. (US) 1984-06-12 US disclosed
EP-0097616-A1 Polyalkylpiperidine esters of sulfonic acids CIBA-GEIGY AG (CH) 1984-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104363-A1 Sulfonate esters as latent acid catalysts ORAI1, SARAF, NAPA TLR8 3066/4885LIPG 991/4885KCNH2 775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.