Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510919 | 0.98 | HRH3 (0.48) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL5507506 | 0.98 | HRH3 (0.48) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL12578821 | 0.93 | HRH3 (0.57) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3437038 | 0.90 | HRH3 (0.62) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL13887133 | 0.88 | HRH3 (0.52) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL14500306 | 0.84 | PAOX (0.54) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6657767 | 0.84 | PAOX (0.54) | HRH3PAOXCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL27100152 | 0.83 | CHKA (0.47) | SIGMAR1PRMT6 | |
| SCHEMBL2616296 | 0.82 | PRMT6 (0.48) | HRH3PAOXSIGMAR1KDM1ACARM1 | |
| SCHEMBL13334876 | 0.82 | HRH3 (0.63) | HRH3SIGMAR1MAPTCARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |