Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 9/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4027265 | 0.91 | PPARA (0.47) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL4035863 | 0.87 | PROKR1 (0.46) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL28754207 | 0.84 | PROKR1 (0.49) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL27616094 | 0.84 | PROKR1 (0.49) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL27616088 | 0.84 | PROKR1 (0.49) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL4032229 | 0.84 | PROKR1 (0.43) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL27635120 | 0.84 | PROKR1 (0.48) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL4031382 | 0.83 | PROKR1 (0.49) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL4030709 | 0.83 | PROKR1 (0.49) | PROKR1NPC1ALDH1A1GAAPPARA | |
| SCHEMBL4033034 | 0.83 | PROKR1 (0.49) | PROKR1NPC1ALDH1A1GAAPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765320-A2 | USE OF PPAR AGONISTS TO TREAT RUMINANTS | Pfizer Products Incorporated (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005115369-A2 | USE OF PPAR AGONISTS TO TREAT RUMINANTS | PFIZER PRODUCTS INC. (US) | 2005-12-08 | — | — | WO | disclosed |