Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974767 | 0.86 | PLAU (0.47) | ANPEPCA1CA2PLAU | |
| SCHEMBL7567926 | 0.86 | PLAU (0.47) | ANPEPCA1CA2PLAU | |
| SCHEMBL11742887 | 0.82 | TSHR (0.41) | IDO1ALDH1A1ANPEPCA1CA2 | |
| SCHEMBL8557409 | 0.77 | NISCH (0.40) | MEN1KMT2A | |
| SCHEMBL5657816 | 0.70 | CYP2A6 (0.44) | ALDH1A1MAPT | |
| SCHEMBL7471519 | 0.70 | IDO1 (0.33) | IDO1ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL6689884 | 0.69 | KDM1A (0.39) | — | |
| SCHEMBL6031591 | 0.67 | MEN1 (0.33) | ALDH1A1LMNAKDM4EMEN1MAPT | |
| Hydrochloric Acid SCHEMBL8690420 | 0.67 | KDM1A (0.50) | ANPEP | |
| SCHEMBL28454918 | 0.67 | HTR2A (0.48) | ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791555-A1 | METHODS FOR TREATING LOCAL TRACHEAL, BRONCHIAL OR ALVEOLAR BLEEDING OR HEMOPTYSIS | Pharmaorigin APS (DK) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006026998-A1 | METHODS FOR TREATING LOCAL TRACHEAL, BRONCHIAL OR ALVEOLAR BLEEDING OR HEMOPTYSIS | PHARMAORIGIN APS (DK) | 2006-03-16 | — | — | WO | disclosed |