Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991998 | 0.78 | CA2 (0.36) | MAOBMEN1KMT2A | |
| SCHEMBL31561634 | 0.78 | ROCK2 (0.38) | MAOBMEN1KMT2A | |
| SCHEMBL28056978 | 0.78 | ESR1 (0.40) | RAB9AMAOB | |
| SCHEMBL3984874 | 0.78 | MALT1 (0.38) | — | |
| SCHEMBL31561635 | 0.78 | ROCK2 (0.38) | MAOBMEN1KMT2A | |
| SCHEMBL30937657 | 0.78 | ROCK2 (0.38) | — | |
| SCHEMBL31561625 | 0.78 | CHRNB4 (0.44) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31561633 | 0.78 | ROCK2 (0.38) | TP53 | |
| SCHEMBL5500714 | 0.77 | IDO1 (0.38) | MEN1KMT2A | |
| SCHEMBL10500702 | 0.76 | NISCH (0.38) | NISCHNPC1RAB9ASIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930562-A | Preparation method of cyclic chiral nitro compound | 北京师范大学 | 2025-05-06 | — | — | CN | disclosed |
| EP-0564358-B1 | 3-aminochromane spiro derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-11-04 | — | — | EP | disclosed |
| US-5420150-A | Antidepressants and treatment of anxiety | GUILLAUMET GERALD (FR) | 1995-05-30 | — | — | US | disclosed |
| US-5397783-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1995-03-14 | — | — | US | disclosed |
| US-5376661-A | Psychological disorders | ADIR ET COMPAGNIE (FR) | 1994-12-27 | — | — | US | disclosed |
| EP-0564358-A1 | 3-aminochromane spiro derivatives, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-10-06 | — | — | EP | disclosed |