Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.46 |
| ▸ | NSD2 | O96028 | 3/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4388559 | 0.86 | HRH3 (0.61) | HRH3NSD2EHMT2PRMT1EHMT1 | |
| Hydrochloric Acid SCHEMBL4385813 | 0.85 | HRH3 (0.46) | HRH3CTSK | |
| SCHEMBL4396105 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL4384562 | 0.82 | HRH3 (0.62) | HRH3MAPT | |
| SCHEMBL4389011 | 0.81 | HRH3 (0.56) | HRH3NSD2EHMT2PRMT1EHMT1 | |
| SCHEMBL4383394 | 0.79 | HRH3 (0.59) | HRH3 | |
| SCHEMBL4388482 | 0.77 | HRH3 (0.45) | HRH3 | |
| SCHEMBL4386356 | 0.77 | HRH3 (0.36) | HRH3NSD2EHMT2PRMT1EHMT1 | |
| SCHEMBL4386358 | 0.77 | HRH3 (0.36) | HRH3NSD2EHMT2PRMT1EHMT1 | |
| SCHEMBL13788007 | 0.76 | HRH3 (0.46) | HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847530-A1 | DIAMINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-10-24 | — | — | EP | disclosed |