Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30369000 | 0.81 | PARP1 (0.64) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL170580 | 0.81 | PARP1 (0.64) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL28394504 | 0.78 | PARP1 (0.55) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL239945 | 0.76 | GSK3B (0.50) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL57038 | 0.74 | PARP1 (1.00) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL2487811 | 0.74 | PARP1 (1.00) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL29038783 | 0.73 | PARP1 (0.95) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL9681519 | 0.73 | PARP1 (0.95) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL9413391 | 0.73 | PARP1 (0.95) | PARP1KMT2AMEN1NPSR1CYP1A2 | |
| SCHEMBL29157626 | 0.73 | PARP1 (0.95) | PARP1KMT2AMEN1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549706-B1 | OPAQUE, COLOUR-PIGMENTED COATING | CIBA SC HOLDING AG (CH) | 2007-01-24 | — | — | EP | claimed |