SCHEMBL239945

SCHEMBL239945

O=C1NC(=O)c2c[nH]cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.50
CASP7 P55210 3/20 0.42
CASP3 P42574 2/20 0.42
CASP6 P55212 2/20 0.42
CASP8 Q14790 2/20 0.42
CASP2 P42575 1/20 0.42
PARP1 P09874 4/20 0.40
PPOX P50336 1/20 0.39
PDGFRA P16234 1/20 0.35
FER P16591 1/20 0.35
LTK P29376 1/20 0.35
CDK8 P49336 1/20 0.35
ACVR1 Q04771 1/20 0.35
LRRK2 Q5S007 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
TDP1 Q9NUW8 4/20 0.33
PRKD3 O94806 4/20 0.33
PRKCG P05129 4/20 0.33
PRKCB P05771 4/20 0.33
PRKCA P17252 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5501068 0.76 PARP1 (0.59) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL2296198 0.72 GSK3B (0.68) GSK3BCASP7CASP3CASP6CASP8
SCHEMBL10904924 0.69 CDC25B (0.47) GSK3BCASP7TDP1CYP3A4KDM4E
Phthalimide SCHEMBL11040503 0.67 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
SCHEMBL278438 0.67 PARP1 (0.59) GSK3BCASP7CASP3CASP6CASP8
SCHEMBL15488741 0.67 GSK3B (0.50) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL7771670 0.67 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL64 0.67 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10192661 0.67 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL15488735 0.65 GSK3B (0.79) GSK3BCASP7CASP3CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115000302-A Source-drain electrode and organic field effect transistor device and preparation method thereof 清华大学 2022-09-02 CN claimed
EP-1781247-B1 COSMETIC COMPOSITIONS CONTAINING FLUORESCENT COLORANTS FOR NATURAL SKIN APPEARANCE BASF SE (DE) 2010-11-03 EP claimed
EP-1470197-B1 MANUFACTURING AND CONDITIONING OF SOLID SOLUTION ORGANIC PIGMENTS BASF SE (DE) 2009-10-14 EP claimed
US-7442731-B2 Opaque, colour-pigmented coating CIBA SPECIALTY CHEMICALS CORP. (US) 2008-10-28 US claimed
EP-1781247-A1 COSMETIC COMPOSITIONS CONTAINING FLUORESCENT COLORANTS FOR NATURAL SKIN APPEARANCE Ciba Specialty Chemicals Holding Inc. (CH) 2007-05-09 EP claimed
EP-1549706-B1 OPAQUE, COLOUR-PIGMENTED COATING CIBA SC HOLDING AG (CH) 2007-01-24 EP claimed
EP-1046681-B1 Hybrid pigments CLARIANT FINANCE BVI LTD (VG) 2006-11-02 EP claimed
EP-1046680-B1 Pigments, the process of their manufacture and their use CLARIANT FINANCE BVI LTD (VG) 2006-07-26 EP claimed
US-7041166-B2 Manufacturing and conditioning of solid solution organic pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-05-09 US claimed
US-20060078518-A1 Cosmetic compositions containing fluorescent colorants for natural skin appearance ELDER STEWART T 2006-04-13 US claimed
EP-0755933-B1 Blue diketopyrrolopyrrole pigments CIBA SC HOLDING AG (CH) 2002-03-27 EP claimed
EP-1046680-A2 Pigments, the process of their manufacture and their use Clariant Finance (BVI) Limited (VG) 2000-10-25 EP claimed
EP-0710705-B1 Yellow diketopyrrolopyrrole pigments CIBA SC HOLDING AG (CH) 1999-12-22 EP claimed
US-5964938-A Pigment granulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-10-12 US claimed
US-5817832-A Blue diketopyrrolopyrrole pigments CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-10-06 US claimed
US-5672716-A Yellow diketopyrrolopyrrole pigments CIBA-GEIGY CORPORATION (US) 1997-09-30 US claimed
EP-0755933-A1 Blue diketopyrrolopyrrole pigments Ciba SC Holding AG (CH) 1997-01-29 EP claimed
EP-0673939-B1 Aminoxide groups containing pyrrolo(3,4-c)pyrroles as photoreceptors CIBA GEIGY AG (CH) 1996-10-23 EP claimed
EP-0710705-A1 Yellow diketopyrrolopyrrole pigments CIBA-GEIGY AG (CH) 1996-05-08 EP claimed
EP-0673939-A1 Aminoxide groups containing pyrrolo(3,4-c)pyrroles as photoreceptors CIBA-GEIGY AG (CH) 1995-09-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060078518-A1 Cosmetic compositions containing fluorescent colorants for natural skin appearance CUTA, MITF, RARA GSK3B 4874/4885CASP7 2007/4885CASP3 3002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.