SCHEMBL5501100

SCHEMBL5501100

CC(C)(C)CCC1CNC(=O)N1CCC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3514840 0.73 MEN1 (0.36)
SCHEMBL8940606 0.69 GLA (0.39)
SCHEMBL3636070 0.69 MEN1 (0.43)
SCHEMBL8394535 0.65 GBA1 (0.43)
SCHEMBL21711071 0.63 GLA (0.34)
SCHEMBL20733168 0.62 GBA1 (0.44)
SCHEMBL3139352 0.62 P2RX7 (0.35)
SCHEMBL20798625 0.62 DAO (0.33) DAO
SCHEMBL14749821 0.61 TSHR (0.36)
SCHEMBL21244695 0.61 AR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1133518-B1 A METHOD FOR THE PREPARATION OF N-NEOHEXYL-(A)-ASPARTYL-L-PHENYLALANINE METHYL ESTER FROM IMIDAZOLIDIN-4-ONE INTERMEDIATES NUTRASWEET CO (US) 2007-01-03 EP disclosed
US-6465677-B1 VIA CONVERSION UNDER REDUCING CONDITIONS OF NOVEL IMIDAZOLIDINONE(S) THE NUTRASWEET COMPANY 2002-10-15 US disclosed
EP-1133518-A1 A METHOD FOR THE PREPARATION OF N-NEOHEXYL-$g(a)-ASPARTYL-L-PHENYLALANINE METHYL ESTER FROM IMIDAZOLIDIN-4-ONE INTERMEDIATES The NutraSweet Company (US) 2001-09-19 EP disclosed
WO-2000031117-A1 A METHOD FOR THE PREPARATION OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER FROM IMIDAZOLIDIN-4-ONE INTERMEDIATES THE NUTRASWEET COMPANY (US) 2000-06-02 WO disclosed