Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867680 | 0.91 | ADORA2A (0.60) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL1138803 | 0.88 | ADORA2A (0.60) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL7752324 | 0.87 | ADORA2A (0.59) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL195449 | 0.85 | ADORA3 (0.57) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL6829360 | 0.85 | ADORA2A (0.57) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL15413277 | 0.83 | ADORA2A (0.55) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL5964932 | 0.82 | CYP2C19 (0.59) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL6630142 | 0.82 | ADORA2A (0.60) | ADORA2AADORA2BSLC29A1ADORA3ADORA1 | |
| SCHEMBL62505 | 0.80 | CYP2C19 (0.62) | ADORA2AADORA2BADORA3ADORA1CYP2C19 | |
| SCHEMBL14931005 | 0.80 | CYP2C19 (0.62) | ADORA2AADORA2BADORA3ADORA1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977767-B1 | AMINOOXY-MODIFIED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS INC (US) | 2007-09-19 | — | — | EP | disclosed |