Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518249 | 0.94 | F10 (0.42) | F10 | |
| SCHEMBL5522177 | 0.93 | F10 (0.43) | F10ITGA4NPC1MAPTNFKB1 | |
| SCHEMBL5507750 | 0.93 | F10 (0.43) | F10ITGA4NPC1MAPTNFKB1 | |
| SCHEMBL5206095 | 0.85 | F10 (0.54) | F10 | |
| SCHEMBL5506356 | 0.84 | F10 (0.41) | F10DGAT1 | |
| SCHEMBL5507739 | 0.83 | F10 (0.42) | F10NPC1MAPTNFKB1RAB9A | |
| SCHEMBL5522170 | 0.83 | F10 (0.42) | F10NPC1MAPTNFKB1RAB9A | |
| SCHEMBL5518282 | 0.82 | F10 (0.42) | F10 | |
| SCHEMBL5509431 | 0.82 | F10 (0.42) | F10 | |
| SCHEMBL4466966 | 0.81 | F10 (0.46) | F10NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747217-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005111029-A1 | NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |