SCHEMBL5518249

SCHEMBL5518249

CON=C1COCCN1c1ccc(NC(=O)C2(N)CCOC2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.42
GAA P10253 1/20 0.34
CNR1 P21554 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5501240 0.94 F10 (0.44) F10
SCHEMBL5507750 0.92 F10 (0.43) F10CNR1CNR2
SCHEMBL5522177 0.92 F10 (0.43) F10CNR1CNR2
SCHEMBL5506356 0.91 F10 (0.41) F10GAACNR1CNR2
SCHEMBL5505701 0.87 F10 (0.39) F10
SCHEMBL3998054 0.86 F10 (0.52) F10
SCHEMBL5504063 0.85 F10 (0.42) F10GAACNR1CNR2
SCHEMBL5507739 0.83 F10 (0.42) F10CNR1CNR2
SCHEMBL5522170 0.83 F10 (0.42) F10CNR1CNR2
SCHEMBL5518282 0.81 F10 (0.42) F10CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747217-A1 NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS Boehringer Ingelheim International GmbH (DE) 2007-01-31 EP disclosed
WO-2005111029-A1 NOVEL SUBSTITUTED THIOPHENECARBOXAMIDES, THEIR PRODUCTION AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2005-11-24 WO disclosed