SCHEMBL5501258

SCHEMBL5501258

O=C(O)c1ccc(I)c(I)c1O.[LiH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
TP53 P04637 1/20 0.43
LDHA P00338 1/20 0.42
CYP1A2 P05177 1/20 0.42
ALDH1A1 P00352 7/20 0.41
KDM4E B2RXH2 4/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 2/20 0.41
ALB P02768 1/20 0.41
MMP2 P08253 1/20 0.41
MAPT P10636 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL606643 0.98 SELL (0.52) SELLSELPTP53LDHACYP1A2
SCHEMBL9482449 0.96 SELL (0.50) SELLSELPTP53LDHACYP1A2
SCHEMBL31615830 0.87 SELL (0.42) SELLSELPTP53LDHACYP1A2
SCHEMBL18585486 0.82 SELL (0.60) SELLSELPTP53LDHACYP1A2
SCHEMBL16097553 0.80 SELL (0.64) SELLSELPTP53LDHACYP1A2
SCHEMBL28219462 0.79 CYP1A2 (0.48) SELLSELPTP53LDHACYP1A2
SCHEMBL625273 0.79 CYP1A2 (0.48) SELLSELPTP53LDHACYP1A2
SCHEMBL10874762 0.78 ALDH1A1 (0.34) SELLSELPTP53ALDH1A1ALOX15
SCHEMBL29072927 0.78 SELL (0.75) SELLSELPLDHACYP1A2ALDH1A1
Hydrochloric Acid SCHEMBL3280994 0.77 CYP1A2 (0.46) SELLSELPTP53LDHACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090042-A1 SINGLE-CELL AND SPATIAL DNA METHYLATION MEASUREMENTS THE BROAD INSTITUTE, INC. (US) 2026-04-30 WO disclosed
US-20240376460-A1 HIGH-THROUGHPUT SINGLE-CELL SEQUENCING WITH REDUCED AMPLIFICATION BIAS ILLUMINA, INC. 2024-11-14 US disclosed
US-11981891-B2 High-throughput single-cell sequencing with reduced amplification bias ILLUMINA, INC. (US) 2024-05-14 US disclosed
US-20230323426-A1 SINGLE CELL WHOLE GENOME LIBRARIES AND COMBINATORIAL INDEXING METHODS OF MAKING THEREOF ILLUMINA INC. (US) 2023-10-12 US disclosed
US-11535883-B2 Single cell whole genome libraries and combinatorial indexing methods of making thereof ILLUMINA, INC. (US) 2022-12-27 US disclosed
EP-1673105-B1 USE OF FOLLICLE STIMULATING HORMONE FOR REDUCTION OF SPERMATOZOA CHROMOSOMAL ABERRATION IN MALES SERONO LAB (CH) 2007-05-02 EP disclosed
US-20070037742-A1 Use of follicle stimulating hormone for reduction of spermatozoa chromosomal aberration in males LABORATORIES SERONO S.A. (CH) 2007-02-15 US disclosed
EP-1673105-A1 USE OF FOLLICLE STIMULATING HORMONE FOR REDUCTION OF SPERMATOZOA CHROMOSOMAL ABERRATION IN MALES LABORATOIRES SERONO S.A. (CH) 2006-06-28 EP disclosed
WO-2005011726-A1 USE OF FOLLICLE STIMULATING HORMONE FOR REDUCTION OF SPERMATOZOA CHROMOSOMAL ABERRATION IN MALES LABORATOIRES SERONO S.A. (CH) 2005-02-10 WO disclosed
CN-1127570-C Application of castor silkworm cell nucleus and skeleton combination elements SHANGHAI INST OF BIOLOG CHEMIS (CN) 2003-11-12 CN disclosed
US-20020073448-A1 Matrix attachment regions NATIONAL SCIENCE FOUNDATION 2002-06-13 US disclosed
EP-1005560-A1 MATRIX ATTACHMENT REGIONS NORTH CAROLINA STATE UNIVERSITY (US) 2000-06-07 EP disclosed
CN-1223299-A Application of castor silkworm cell nucleus and skeleton combination elements SHANGHAI INST OF BIOLOG CHEMIS (CN) 1999-07-21 CN disclosed
WO-1999007866-A1 MATRIX ATTACHMENT REGIONS NORTH CAROLINA STATE UNIVERSITY (US) 1999-02-18 WO disclosed
US-4906571-A Cell surface modification using a novel glycoproteinase of pasteurella haemolytica UNIVERSITY OF GUELPH (CA) 1990-03-06 US disclosed