Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 4/20 | 0.55 |
| ▸ | FBP1 | P09467 | 2/20 | 0.55 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.55 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.55 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.55 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.55 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.55 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469888 | 1.00 | P2RY2 (0.55) | P2RY2FBP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL17789098 | 1.00 | P2RY2 (0.55) | P2RY2FBP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL16489876 | 1.00 | P2RY2 (0.55) | P2RY2FBP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL17809091 | 1.00 | P2RY2 (0.55) | P2RY2FBP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL14946156 | 1.00 | P2RY2 (0.55) | P2RY2FBP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL903023 | 1.00 | P2RY2 (0.55) | P2RY2FBP1DNPH1PRKAB2TRPM2 | |
| SCHEMBL625445 | 0.90 | P2RY2 (0.62) | P2RY2P2RY1P2RY11P2RY6P2RY4 | |
| SCHEMBL3503039 | 0.90 | P2RY2 (0.62) | P2RY2P2RY1P2RY11P2RY6P2RY4 | |
| SCHEMBL21742739 | 0.90 | P2RY6 (0.66) | P2RY6P2RY14NT5E | |
| SCHEMBL11511464 | 0.88 | P2RY2 (0.56) | P2RY2FBP1DNPH1PRKAB2TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828750-B1 | PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE | EC TECHNOLOGY LLC (US) | 2013-07-17 | — | — | EP | disclosed |
| EP-0828750-A4 | PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE | EC TECHNOLOGY LLC (US) | 2007-11-07 | — | — | EP | disclosed |
| US-5945527-A | REACTING CYTOSINE CONTAINING A LEAVING GROUP ATTACHED TO 5- OR 6-POSTION OF MOLECULE, ISOLATING MODIFIED NUCLEOSIDE; FOR NOVEL FUNGICIDES, VIRICIDES, BACTERICIDES, ANTITUMOR AGENTS | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-08-31 | — | — | US | disclosed |
| EP-0828750-A1 | PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE | NeXstar Pharmaceuticals, Inc. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038460-A1 | PALLADIUM CATALYZED NUCLEOSIDE MODIFICATION METHODS USING NUCLEOPHILES AND CARBON MONOXIDE | NEXSTAR PHARMACEUTICALS, INC. (US) | 1996-12-05 | — | — | WO | disclosed |