Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 10/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781868 | 0.92 | DRD4 (0.43) | DRD2DRD4DRD3HTR2A | |
| SCHEMBL2785586 | 0.89 | DRD2 (0.48) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL5502725 | 0.80 | DRD2 (0.40) | DRD2DRD4DRD3HTR2AHTR1A | |
| SCHEMBL2784121 | 0.79 | DRD2 (0.54) | DRD2DRD4DRD3 | |
| SCHEMBL2785322 | 0.78 | DRD2 (0.42) | DRD2DRD4DRD3HTR2A | |
| SCHEMBL2781897 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL2781919 | 0.78 | DRD2 (0.48) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL2785380 | 0.77 | DRD2 (0.49) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL2781201 | 0.76 | DRD4 (0.47) | DRD2DRD4DRD3 | |
| SCHEMBL5502922 | 0.76 | DRD2 (0.39) | DRD2DRD3HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773772-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2007-04-18 | — | — | EP | claimed |
| WO-2005121087-A1 | NEW DISUBSTITUTED PHENYLPIPERIDINES/PIPERAZINES AS MODULATORS OF DOPAMINE NEUROTRANSMISSION | A. CARLSSON RESEARCH AB (SE) | 2005-12-22 | — | — | WO | claimed |