Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.69 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cycloheptane SCHEMBL5493970 | 0.87 | ADORA2A (0.66) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| Cycloheptane SCHEMBL5502824 | 0.87 | RAB9A (0.59) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| Cycloheptane SCHEMBL5501393 | 0.87 | ADORA2A (0.66) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4287595 | 0.85 | ADORA2A (0.62) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1119373 | 0.83 | RAB9A (0.71) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4290407 | 0.82 | ADORA2A (0.68) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4293148 | 0.82 | ADORA2A (0.74) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4290911 | 0.82 | RAB9A (0.77) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4289795 | 0.81 | ADORA2A (0.73) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3189489 | 0.81 | ADORA2A (1.00) | ADORA2AADORA1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682129-B1 | N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2007-02-21 | — | — | EP | claimed |