Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA7 | P43166 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5840102 | 0.80 | NPC1 (0.46) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL6948735 | 0.80 | NPC1 (0.46) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL3546411 | 0.79 | SMN1; SMN2 (0.39) | IRAK4ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10700176 | 0.79 | NPC1 (0.45) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL137907 | 0.74 | NPC1 (0.62) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL2942817 | 0.73 | IRAK4 (0.66) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL9673372 | 0.72 | CA1 (0.37) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7615528 | 0.71 | IRAK4 (0.64) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL6014143 | 0.71 | IRAK4 (0.64) | NPC1CA12CA1CA2CA7 | |
| SCHEMBL1033621 | 0.71 | IRAK4 (0.64) | NPC1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827416-A1 | PHARMACEUTICAL COMPOSITIONS | Abbott Laboratories (US) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006060817-A1 | PHARMACEUTICAL COMPOSITIONS | ABBOTT LABORATORIES (US) | 2006-06-08 | — | — | WO | disclosed |
| EP-1517676-A1 | ORAL DOSAGE FORMS COMPRISING FENOFIBRATE | SKYEPHARMA CANADA INC. (CA) | 2005-03-30 | — | — | EP | disclosed |
| WO-2003092659-A1 | ORAL DOSAGE FORMS COMPRISING FENOFIBRATE | SKYEPHARMA CANADA INC. (CA) | 2003-11-13 | — | — | WO | disclosed |