Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA7 | P43166 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942817 | 0.98 | IRAK4 (0.66) | IRAK4NPC1ALDH1A1ACHEIDO1 | |
| SCHEMBL11465655 | 0.96 | IRAK4 (0.64) | IRAK4NPC1ALDH1A1ACHEIDO1 | |
| SCHEMBL6014143 | 0.96 | IRAK4 (0.64) | IRAK4NPC1ALDH1A1ACHEIDO1 | |
| SCHEMBL1033621 | 0.96 | IRAK4 (0.64) | IRAK4NPC1ALDH1A1ACHEIDO1 | |
| SCHEMBL27958806 | 0.85 | IRAK4 (0.68) | IRAK4NPC1ALDH1A1ACHEIDO1 | |
| SCHEMBL1071954 | 0.84 | HPGD (0.58) | NPC1ALDH1A1KCNK3KCNK9HPGD | |
| SCHEMBL4036585 | 0.84 | IRAK4 (0.66) | IRAK4ALDH1A1ACHEIDO1TDO2 | |
| SCHEMBL30628008 | 0.83 | HPGD (0.59) | IRAK4NPC1ALDH1A1IDO1TDO2 | |
| SCHEMBL28073864 | 0.83 | HPGD (0.59) | IRAK4NPC1ALDH1A1IDO1TDO2 | |
| SCHEMBL15814203 | 0.83 | IRAK4 (0.51) | IRAK4NPC1ALDH1A1ACHEIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816324-B1 | Subsituted benzyl derivatives of polyalkylene-polyamines and their use in cosmetic and pharmaceutical compositions | OREAL (FR) | 2000-02-16 | — | — | EP | claimed |
| US-5910513-A | PROTECTING THE BODY AGAINST OXIDATIVE STRESS SUCH AS NEURODEGENERATIVE DISEASES, PARKINSON'S DISEASE, CHRONIC INFLAMMATORY CONDITIONS, REINFUSION ISCHAEMIA SYNDROME, THE TOXICITY OF CERTAIN DRUGS SUCH AS CERTAIN XENOBIOTICS | L'OREAL (FR) | 1999-06-08 | — | — | US | claimed |
| WO-2002102342-A1 | NO-SYNTHASE INHIBITOR AND USES THEREOF | L'OREAL (FR) | 2002-12-27 | — | — | WO | disclosed |
| US-6482855-B2 | OXIDATION RESISTANCE; STRESS RELIEVING | L'OREAL S.A. (FR) | 2002-11-19 | — | — | US | disclosed |
| US-20010016592-A1 | Novel diamine alkylene diacetic or triacetic acid derivatives, preparation method, use in cosmetic and pharmaceutical compositions and compositions containing them | L'OREAL S.A. | 2001-08-23 | — | — | US | disclosed |
| US-6258847-B1 | Use of 2-mercaptoethanolamine (2-MEA) and related aminothiol compounds and copper(II)-3,5 di-isopropyl salicylates and related compounds in the prevention and treatment of various diseases | CHACHOUA SAMIR (AU) | 2001-07-10 | — | — | US | disclosed |
| US-6218432-B1 | FOR PROTECTING BODY AGAINST OXIDATIVE STRESS | L'OREAL (FR) | 2001-04-17 | — | — | US | disclosed |
| US-5929112-A | USE IN PHARMACEUTICALS OR COSMETICS AS ANTIOXIDANTS, IMPROVED BIOAVAILABILITY | L'OREAL (FR) | 1999-07-27 | — | — | US | disclosed |
| US-5910513-A | PROTECTING THE BODY AGAINST OXIDATIVE STRESS SUCH AS NEURODEGENERATIVE DISEASES, PARKINSON'S DISEASE, CHRONIC INFLAMMATORY CONDITIONS, REINFUSION ISCHAEMIA SYNDROME, THE TOXICITY OF CERTAIN DRUGS SUCH AS CERTAIN XENOBIOTICS | L'OREAL (FR) | 1999-06-08 | — | — | US | disclosed |
| EP-0858327-A2 | USE OF 2-MERCAPTOETHANOLAMINE (2-MEA) AND RELATED AMINOTHIOL COMPOUNDS AND COPPER(II)-3,5 DI-ISOPROPYL SALICYLATES AND RELATED COMPOUNDS IN THE PREVENTION AND TREATMENT OF VARIOUS DISEASES | Chachoua, Samir (AU) | 1998-08-19 | — | — | EP | disclosed |
| US-5760037-A | SKIN AGING, RADIATION AND OXIDATION RESISTANCE; FREE RADICALSCAVENGERS | L'OREAL (FR) | 1998-06-02 | — | — | US | disclosed |
| WO-1997011666-A2 | USE OF 2-MERCAPTOETHANOLAMINE (2-MEA) AND RELATED AMINOTHIOL COMPOUNDS AND COPPER(II)-3,5 DI-ISOPROPYL SALICYLATES AND RELATED COMPOUNDS IN THE PREVENTION AND TREATMENT OF VARIOUS DISEASES | CHACHOUA SAMIR (MX) | 1997-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016592-A1 | Novel diamine alkylene diacetic or triacetic acid derivatives, preparation method, use in cosmetic and pharmaceutical compositions and compositions containing them | DDC, AADAC, AADAT | IRAK4 4092/4885NPC1 2932/4885ALDH1A1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.